Red Reishi Helps Hamsters Lower Cholesterol!
IF YOU FIND THIS ARTICLE HELPFUL SHARE AND HELP OTHERS!
Red Reishi Useful For Lowering Cholesterol?
1Nestlé Research Center, Lausanne 26, 1000, Switzerland. [email protected]
There has been renewed interest in mushroom medicinal properties. We studied cholesterol lowering properties of Ganoderma lucidum/red reishi (Gl), a renowned medicinal species.
Organic fractions containing oxygenated lanosterol derivatives inhibited cholesterol synthesis in T9A4 hepatocytes. In hamsters, 5% Gl did not effect LDL; but decreased total cholesterol (TC) 9.8%, and HDL 11.2%. Gl (2.5 and 5%) had effects on several fecal neutral sterols and bile acids. Both Gl doses reduced hepatic microsomal ex-vivo HMG-CoA reductase activity. In minipigs, 2.5 Gl decreased TC, LDL- and HDL cholesterol 20, 27, and 18%, respectively (P < 0.05); increased fecal cholestanol and coprostanol; and decreased cholate.
Overall, Gl has potential to reduce LDL cholesterol in vivo through various mechanisms. Next steps are to: fully characterize bioactive components in lipid soluble/insoluble fractions; evaluate bioactivity of isolated fractions; and examine human cholesterol lowering properties. Innovative new cholesterol-lowering foods and medicines containing Gl are envisioned.
Reishi On Wikipedia
ENJOYING OUR POSTS?
If you are finding our posts helpful and informative why not sign up to our newsletter. You'll receive medicinal mushroom articles and product updates and exclusive member discounts at the store. Plus 15% OFF your first order :)
To buy organic red Reishi extract
Trackback from your site.